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Acifar (Acyclovir)
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Acyclovir

Acifar is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection. It can be taken by mouth, applied as a cream, or injected.Common side effects include nausea and diarrhea. Potentially serious side effects include kidney problems and low platelets. Greater care is recommended in those with poor liver or kidney function. It is generally considered safe for use in pregnancy with no harm having been observed. It appears to be safe during breastfeeding. Acifar is a nucleoside analogue that mimics guanosine. It works by decreasing the production of the virus's DNA.Acifar was patented in 1974, and approved for medical use in 1981. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication and is marketed under many brand names worldwide. The wholesale cost as of 2014 to 2016 was between US$0.03 and US$0.12 for a typical dose by mouth. The cost of a typical course of treatment in the United States is less than US$25. In 2016 it was the 195th most prescribed medication in the United States with more than 3 million prescriptions.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Perception of Learning Environment among Undergraduate Medical Students in Two Different Medical Schools through DREEM and JHLES Questionnaire. I/R induced intestinal apoptosis was significantly attenuated in PUMA knockout mice compared with that in wild-type mice. Why voxel-based morphometric analysis should be used with great caution when characterizing group differences.

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Without training-based diagnosis (unsupervised learning), the vbMFA identified four important patterns of field loss in eyes with GON in a manner consistent with years of clinical experience. We compared sleep EEG characteristics of 7 children with typical LKS to those of 6 children with classical BECTS. Mutation of the - 165 bp Egr-1 and - 48 bp Sp1 sites, respectively, attenuated and abolished combined forskolin and PMA-mediated promoter activation. Animals were sacrificed at 7, 28, and 84 days postoperatively and specimens investigated using electron microscopy and electron dispersive X-ray analysis. The antiproliferative and antiangiogenic properties of EF24 provide theoretical support for its development and application to liver cancers.

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Results for the spectral function, optical conductivity, and the paramagnetic-to-ferromagnetic phase transition show that electronic correlations have drastic effects and may explain some experimental observations. The nucleus of the eukaryotic cell must carry out many functions simultaneously. These results suggest that there is a close relationship between polyamine and fetal development, and putrescine may play an important role as the trigger in fetal development. Histologically, the disease in both strains was characterized by cellular infiltration and multifocal demyelination in the CNS.

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However, the potent effect of 1,25-(OH)2D3 on intestinal calcium and phosphorus absorption and bone mineral mobilization often leads to the development of hypercalcemia and hyperphosphatemia precluding 1,25-(OH)2D3 therapy. We demonstrate that this effect is identical to that of a standard electrostatic biprism.

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CoA binding to one entrance of the channel promotes a conformational change in the channel, resulting in the opening of the opposite dihydrolipoamide gate. Vessel wall response by histological analysis and SEM was similar in both groups. Following initial small-molecule studies, the reaction was performed on two protein substrates. Subjects completed a visual analog scale and Likert scale of muscle soreness every morning and evening for the 5 days following their race. Surgical treatment of nonfunctioning islet cell tumor: report of 41 cases.

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Serum human telomerase reverse transcriptase messenger RNA as a novel tumor marker for hepatocellular carcinoma. DHF did not alter the ability of the afferent volley to generate a synaptic potential, but it did impair the ability of the synaptic potential to elicit a population spike. 1.9.E labeled the ONL and glomerular layer of the olfactory bulb (OB) of adult rats. Hepatocellular carcinoma (HCC) is one of the most common human malignancies. Such research may be accomplished through collaborations among specialists from various related disciplines and, importantly, with active involvement of community partners.

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Absorption rate profiles for theophylline obtained by the method using published data gave information on the initiation and termination of the absorption as well as the extent of absorption from the dosage form. The insular perforating arteries originate from the middle cerebral artery. Among all the common coated antigens, it was found that PPD was the most potential one. Significant hemodynamic modifications were not observed and their neurological conditions improved.

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Such knowledge will enable determination of which critical molecular pathways should be targeted by potential therapeutic agents developed for the treatment of tauopathies. Both expressions are markedly increased in the infarcted heart and the levels of TGF-beta(1) mRNA precedes increases in mRNA levels for extracellular matrix (ECM) proteins, suggesting a possible role of TGF-beta(1) in remodeling processes in the myocardium. Mortality was related primarily to the underlying severity of illness.

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Plasmid DNA and viral vector-based cancer vaccines have many inherent features that make them promising cancer vaccine candidates. Effect of non-steroid anti-inflammatory agents on the course of allergic myocarditis The activation of kainate receptors (KR) located in the presynaptic terminal of the interneurons reduces GABAergic synaptic transmission at the interneuron principal cell synapse in the CA1 layer of the hippocampus. In this sense, CS-1 could be a good candidate because it is expressed preferentially in heart, to a lesser extent in smooth muscle cells, but not in kidney. For a period of over two years 99 volunteer healthy homosexual men were examined periodically for the presence of interferon (IFN) in their serum.

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We retrospectively analyzed our experience with extended multiorgan resection (EMR) in patients with advanced gastric cancer. Synchronous hepatic cryotherapy and resection of colonic primary is a high risk procedure. Functional ameloblasts are tall, columnar, polarized cells that synthesize and secrete enamel-specific proteins. Histological slides of bone marrow biopsy specimens and aspirates from 32 adult patients with severe primary ITP who had failed a median of two treatments, and 51 non-thrombocytopenic controls were retrieved from hospital archives. The article describes a method of teaching in which mainstream biomedical learning is linked to digressions, which serve as the medium for considering the contexts of medicine, unmasking hidden messages, and broadening the scope of medical instruction.

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Aberrant angiogenesis and localized inflammation contribute to the formation of CSDH. However, the safety use of dexamethasone has been questioned recently because of the risk of secondary adrenal deficiency. Between October 2010 and January 2013, 72 patients referring to the outpatient clinic of the Rehabilitation Department of the Trauma Center, University Hospital of Careggi, Florence, have been enrolled if a primary gonarthrosis was diagnosed. We investigated the relationships between the MAOA polymorphism, trait aggression, trait interpersonal hypersensitivity, and neural responses to social exclusion in 32 healthy men and women.

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Plate fixation for Letenneur type I Hoffa fracture: a biomechanical study. Data from the Survey of Income and Program Participation indicate that 50.7 million individuals lacked health insurance coverage for at least one month during calendar year 1992. Molecular diagnosis of resistance to antimalarial drugs during epidemics and in war zones. Security systems keep tabs on patients, guard against abduction, aid rehab and heighten peace of mind among caregivers.

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To address this we have examined Ltbp1 promoter activity throughout mammary development using an Ltbp1L-LacZ reporter as well as expression of both Ltbp1L and 1S mRNA and protein by qRT-PCR, immunofluorescence and flow cytometry. Rheumatoid arthritis treated by norethynodrel associated with mestranol: clinical aspects and laboratory tests A case of a myocardial infarction after a wasp sting in a 39-year old man is reported.

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Problems of the cancer and tuberculosis from the statistical point of view We retrospectively reviewed patients with unresectable melanoma or sarcoma hepatic metastasis treated with PHP from 2008 to 2013 and evaluated therapeutic response, morbidity, hepatic progression free survival (hPFS), and overall survival (OS). However, measurement of weight gain and/or serum concentrations of urea nitrogen and albumin clearly showed a beneficial effect of methionine supplementation at protein concentrations of 2.2 and 2.6 g/100 kcal.

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For periodic modulations of the wall temperature the bubble oscillates about the steady state. The prevalences of difficulties in jaw opening, loss of anterior teeth due to trauma, and masticatory problems were greater in men than in women. Based on extensive mutations and BIAcore studies, we show that the higher potency and site 1 affinity of hGH for the pGHR is primarily a result of a decreased off-rate associated with residues in the extended loop between helices 1 and 2 that interact with the two key tryptophans Trp104 and Trp169 in the receptor binding hot spot. Campath-1H (alemtuzumab), a humanised anti-CD52 monoclonal antibody, is a potent therapeutic agent against advanced CLL and immune cytopenias. A 20-year follow-up of the male population of the Rhondda Fach, examined in 1950-1, has been completed.

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