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Antabuse (Disulfiram)

Antabuse, a drug used in the treatment of alcohol dependence, is an inhibitor of dopamine-β-hydroxylase causing an increase in the concentration of dopamine in the mesolimbic system. In addition to the physical symptoms associated with concomitant use of alcohol, Antabuse may lead to adverse events, when used alone, including psychosis. Aims. To report a case of a rare complication when using Antabuse for alcoholism treatment in a patient in alcoholic abstinence. Case Report. We describe the case of a 42-year-old male patient, who developed psychotic symptoms 3 weeks after initiating treatment with Antabuse for alcohol dependency. The patient had a history of chronic alcoholism for 12 years and was under Antabuse treatment (250 mg/day) for 1 month, with no other past history of psychiatric illness. The symptoms worsened after he initiated alcohol consumption, while taking Antabuse. The patient was hospitalized and Antabuse was suspended. After 4 days he was asymptomatic and at 6-week follow-up remained asymptomatic.

Other names for this medication:
Disulfiram, Antabuse, Anticol, Aversan, Esperal, Etabus, Tenutex,

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Immunochemical studies indicated that the polyclonal antibody raised against MS1 blocked the growth-promoting effect elicited by the bone-conditioned media. The prolactin secretory response to subcutaneous injection of orphanin FQ/nociceptin (OFQ/N) was measured in wild-type and OFQ/N knockout mice.

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Distribution of free amino acids and related substances in organs of the rat. Allelochemical effects of volatile compounds and organic extracts from Muscodor yucatanensis, a tropical endophytic fungus from Bursera simaruba. A retrospective analysis is made of 61 patients with clinical and histological diagnosis of pure sarcomas of the jaw treated between 1950 and 1984. Among tested drugs, cefoxitin and tigecycline showed promising in vivo activity against M. Community-based approaches and partnerships: innovations in health-service delivery in Bangladesh.

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The anatomy, cause, and surgical treatment of lumbar hernia are reviewed. Compulsory premarital screening for the human immunodeficiency virus. The results showed that transitional areas contribute to the polycyclic aromatic hydrocarbon accumulation in the sediment turning it into a trap. Recent data have revealed that the mitotic spindle might form by centrosome-independent mechanisms, even in centrosome-containing cells. At the same time, studies suggest a protective role of diabetes in the development of abdominal aortic aneurysms.

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The challenge of eradication: lessons from past eradication campaigns. Improved oral absorption and chemical stability of everolimus via preparation of solid dispersion using solvent wetting technique. Development and validation of a pediatric severity index for sickle cell patients. Molecular mechanism of osteochondroprogenitor fate determination during bone formation.

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Its components were a serine protease (a thrombin-like enzyme) extracted from the venom of Crotalus durissus terrificus snakes and a fibrinogen-rich cryoprecipitate extracted from the blood of Bubalus bubalis buffaloes. The esterase isozymes of 432 strains of foxtail millet, Setaria italica (L.) P. Transposon vectors for gene-trap insertional mutagenesis in vertebrates.

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The two groups were well matched for age, burn size, and inhalation injury. Small RNA clusters from protein-coding genes where a TE is present within one kilobase show a different predominant inheritance pattern (additive) from those that do not (low-parent dominance).

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We describe three cases of ZIKV-infected breastfeeding mothers who were symptomatic within three days of delivery, and two cases with ZIKV-infected newborns. Although cells grown on both surfaces exhibited good adhesion capabilities, a well-differentiated osteoblastic phenotype, and maintained a clear proliferation potential, our study suggests that plasma-sprayed treatment offers a better performance than SLA by creating, at least in the early phases, better conditions for tissue healing.

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To compare the efficacy of hydroxychloroquine, penicillamine, sodium aurothiomalate and auranofin in the treatment of active rheumatoid arthritis over a period of 5 yr. A quality-improvement intervention, including education, central venous catheter (CVC) insertion bundle, process and outcome surveillance, have been introduced since March 2013. This review discusses the principals of human cardiac MRS and literature pertaining to use of MRS in patients with cardiomyopathy. The integration with other Python software makes StochPy both a user-friendly and easily extendible simulation tool.

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Multiple binding sites in fibrinogen for integrin alphaMbeta2 (Mac-1). Surgery, especially solid organ transplantation, may offer unique experimental models in which it is ethically acceptable to gain information on difficult problems of amino acid and protein metabolism. The breeding of piglets free of infection and the development of infection-free pig farms in Baden-Wurttemberg Confirmation was provided by cross-sectional echocardiography and positive blood culture.

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PONV and pain were evaluated in 29 boys during the first 24 h after daycase penile surgery. Unusual dissemination of cancer of the stomach with skin metastases

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The authors provide representative cases of patients with thoracolumbar trauma who underwent MIS surgery utilizing the MIS trauma treatment algorithm. However, there is continued controversy surrounding the terminology used to describe patients with heart failure and the criteria used to make the diagnosis of diastolic heart failure. Headache and musculo-skeletal pain are major public health problems. Culture-dependent and -independent techniques were used to study the diversity of chemolithoautotrophic sulfur-oxidizing bacteria in Soap Lake (Washington State), a meromictic, haloalkaline lake containing an unprecedentedly high sulfide concentration in the anoxic monimolimnion. STS has developed a composite mortality and morbidity outcomes measure for isolated AVR to be used in quality assessment, provider feedback, public reporting, and performance improvement.

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