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Clora (Clomipramine)
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Clomipramine

Clora is a psychotropic agent used to treat obsessive-compulsive disorder (OCD). Clora shares structural similarities with a class of antidepressants known as tricyclic antidepressants (TCAs). The exact mechanism by which Clora exerts its therapeutic benefits is not fully understood. However, similar to other TCAs, Clora is thought to enhance the actions of norepinephrine and serotonin (chemical neurotransmitters in the brain that nerves use to communicate with one another) by blocking their reuptake and prolonging their activity. Clora also has anticholinergic properties which means it blocks the action of another neurotransmitter, acetylcholine. This increases the risk for certain side effects. It also has weak antihistamine properties which appear to play a role in the mild sedative effects observed with use. Clora was approved by the US FDA for the treatment of OCD in 1991.

Other names for this medication:
Clomipramine, Anafranil, Clofranil, Clomipramina, Clora, Zenil,

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Whole-genome expression profiling has been used to characterize molecular-level differences between psoriasis lesions and normal skin. Seven known bisindoles (6-12) were concomitantly obtained from them. In addition, the sphygmus system should be modeled physically and mathematically.

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Sacral resection disrupts the continuity between the spine and pelvis, resulting in loss of skeletal support for weight bearing. The primary infection with varicella-zoster virus (VZV) is manifest clinically as varicella. Inoculation of cells of the Walker tumor into the spleen of the rat. Antibiotics and antifungals could not control or cure this disease, so education for people at high risk is advocated. In this paper we present a new software toolkit for generating and optimizing surface and volumetric meshes from three-dimensional (3D) biomedical imaging data, targeted at image-based finite element analysis of some biomedical activities in a single material domain.

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Thus a deficiency in one system does not necessarily leave the polymorphs completely incapable of antimicrobial action although impairment may be severe as in chronic granulomatous disease. The bronchus intermedius arose directly from the trachea in place of the right main bronchus. The examination of 39 members (age older than 35) belonging to the families of the 7 patients with unilateral hypertensive uveitis and with familial history of primary glaucoma emphasized 13 cases of glaucoma and 5 cases suspicious of glaucoma. In addition, 429 Turkish and Moroccan parents were questioned about hepatitis A vaccination of their children when travelling to their country of origin. Here, using optogenetic circuit analysis and cell type-specific deep-brain recordings in behaving mice, we show that orexin cell activation rapidly recruits GAD65LH neurons.

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The present report emphasizes that stereotactic mesencephalotomy, if performed meticulously and precisely, is a safe surgical procedure for pain relief. Comparing the calcium binding abilities of two soybean calmodulins: towards understanding the divergent nature of plant calmodulins. The purpose of this study was to correlate intraoperative blood flow measurements with outcome in vascular access surgery.

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Binding studies revealed that similar to the full-length Smad protein, both MH1 and MH2 associate with Tat protein and that the residues between 1 and 40 of Tat are important for their interaction. Without bone ingrowth, stress transfer to bone adjacent to the collar increased with collar angle.

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Rubralactone, rubralides A, B and C, and rubramin produced by Penicillium rubrum. Linkage disequilibrium between S65C HFE mutation and HLA A29-B44 haplotype in Terceira Island, Azores. This review examines recent functional neuroimaging research of resting-state regional connectivity between brain regions in anxiety disorders. The purpose was to describe beliefs about tobacco use and cessation among current and former tobacco users in rural Appalachia using focus groups. Organocatalytic hydride transfers: a new concept in asymmetric hydrogenations.

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Sleep prepares key neural structures for next-day learning, and sleep obtained after learning promotes subsequent memory consolidation supporting long-term retention. Dielectric studies of the hydrogen bond and of the helix-coli polypeptide structure.

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The prevalence of falls is high in this population of persons with MS, and the impact of MS and of fatigue is greater in fallers. Time of day as a factor in collision-involvement of drunken drivers.

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Through the incision in the double-eyelid fold, a tunnel was dissected upward from the plane under the orbicular muscle to reach the brow incision. Impact of hospital infection on medical expenditures in a continuing care and rehabilitation service at a geriatric hospital The Impact of Carbon Surface Composition on the Diffusion and Adsorption of Paracetamol at Different Temperatures and at Neutral pH.

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Conformal radiotherapy plus local hyperthermia in patients affected by locally advanced high risk prostate cancer: preliminary results of a prospective phase II study. The coupled mode theory is employed to explain the Fano resonance effect, and the analytical result is in good agreement with the simulation result. Demonstration of slide projection as an alternative to imaginal stimulus presentation in systematic desensitization therapy. Human urinary excretion of orally administered anisotropine methylbromide.

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However, a positive correlation between lGI and local connectivity was present in all four clusters in patients with ASD. There was large variation in odour, and samples clustered in two groups, one with low odour and high pH (above 6.5), the other with high odour and low pH (below 6.0). Among five gastrinomas, three tumours were moderately stained and two tumours were more weakly stained for cdk6 and p16. The nutritional goal is defined by multiplication of the base rate, i.e. The aggregates persist even on 7,000-fold dilution in ion-free water.

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Prototype curriculum for a fellowship in emergency medical services. Renal delivery of l-DOPA and urinary excretion of l-DOPA significantly decreased while dopamine and metabolites were not affected.

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Laryngeal function recovered totally in 10 patients and partially in 2 patients with laryngeal stenosis. The objective of this study was to evaluate the role of local oxygen tension in the zone-specific hepatotoxicity due to allyl alcohol. Determination of pentachlorophenol in wood samples using liquid chromatography with UV absorbance, amperometric and electron-capture detection.

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We report a 58 years old male with a four years history of hemoptysis and renal dysfunction characterized by hematuria and proteinuria, responsive to steroidal therapy. Associated perinephric abscess and passage of fungus balls in the urine.

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Complications do not appear to be appreciably higher in the RSA group in the existing follow-up. The fibrosis associated with endocardial ICD leads and the cumulative acute damage produced by defibrillation discharges may explain changes in the defibrillation and pacing thresholds and the difficulty of lead extraction that can be encountered with transvenous ICD systems. Therapeutic effect of in vivo transfection of transcription factor decoy to NF-kappaB on septic lung in mice. Alterations in the signal cascade of pathological myocardial growth, including humoral stimuli, receptors, intracellular messengers or transcriptional factors, may be favourably modified at different levels.

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Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism. Local platelet consumption in erythromelalgic areas became evident by the demonstration of arteriolar fibromuscular intimal proliferation and occlusions by platelet-rich thrombi in skin biopsies, by the findings of shortened platelet survival times, significant higher levels of platelet activation markers beta-thromboglobulin, thrombomoduline and increased urinary thromboxane B2 excretion in thrombocythemia patients suffering from erythromelalgia. The aims and objectives of the program are presented, along with the overall program structure, entry, registration, and attendance requirements. 4T00.1-conditioned medium did not stimulate the growth of primative erythroid (BFU-E) and multilineage (CFU-GEMM) colonies, but stimulated the growth of FDC-P1 cells, thereby establishing the activity produced by 4T00.1 cells as GM-CSF.

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Pulmonary embolism is a rare but serious complication following shoulder arthroscopy. Experimental proof on origination of posterior pituitary hormones in the hypothalamus

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These findings highlight nonenzymatic roles of a major HDAC in transcriptional regulation in vivo and warrant reconsideration of the mechanism of action of HDAC inhibitors. Very few plastids and mitochondria of male origin were observed around the fusing sperm and egg nuclei, while the retained sperm nucleus was surrounded by a large amount of male cytoplasm. From September 2004 till September 2008, 222 treatment-naive patients were enrolled and divided into 2 arms: 114 arm A patients were treated with leucovorin, 5-fluorouracil plus irinotecan in combination with bevacizumab, and 108 arm B patients were treated as above without bevacizumab. These observations suggested that a combination of endoglin DNA and recombinant protein immunization as a vaccine strategy was superior to those using endoglin DNA or recombinant protein alone as vaccines. The differential diagnosis is essentially the leiomyosarcoma which is characterized by the absence of mitotic activity.

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With the exception of Zellknorpel, all the tissues previously described in teleost heads were present in the trunk and fins, although they were found in smaller quantities. To establish a diagnostic test for familial Mediterranean fever. Prostate Cancer: Diffusion-weighted MR Imaging for Detection and Assessment of Aggressiveness-Comparison between Conventional and Kurtosis Models.

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Deployment of balloon expandable stents during open repair of thoracoabdominal aortic aneurysms: a new strategy for managing renal and mesenteric artery lesions. Cold-staining of tubercle bacteria with the aid of surface-acting substances From the bone marrow of Sprague-Dawley rats, mesenchymal stem cells were isolated and expanded.

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Dietary phenylalanine had no significant effect on serum phenylalanine for either twin. Cytotoxic activities of splenocytes were higher in IL-21 secreting RenCa cell rejected mice than in parental RenCa mice. Recurrence pattern of esophageal cancer after esophagectomy with two-field lymphadenectomy. Diabetes, tardive dyskinesia, parkinsonism, and akathisia in schizophrenia: a retrospective study applying 1998 diabetes health care guidelines to antipsychotic use. Transformation between Kaposiform hemangioendothelioma and tufted angioma.

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A circadian clock in the olfactory bulb controls olfactory responsivity. The anharmonic ro-vibrational spectra of HgBrO and HgClO have been calculated in variational calculations. An egg-free and broadly effective influenza vaccine that can be produced rapidly, adequately and cost-effectively is needed. Advanced methods for handling and preparation of stallion semen.

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Insulin injection technique has far greater bearing on glycaemic control than is often recognised. The radiochemical purity of the (99m)Tc-labeled MAG3 kit was tested under different storage conditions.

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To define the role of C/EBPbeta or Nrf2 repression in GST expression under the condition excluding the negative regulation by C2-mediated HNF1 suppression, luciferase activity was determined in the cells transfected with DeltaHNF-pGL-1651 plasmid lacking the HNF1-response element. The effects of Chinese herb Angelica in focal cerebral ischemia injury in the rat. Nevertheless, in the last 30 years major advances have resulted in characterization of a number of vaccine candidates, exploration of the repertoire of host immune responses to the various parasite stages, and also identification of significant hurdles that need to be overcome. Leprosy developing over 7 years, having presented 5 reactional outbreaks in renal form Microbial populations associated with commercially produced South African sorghum beer as determined by conventional and Petrifilm plating.

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Ventral shifting of the dorsal part of the cloaca was observed until E12.5. Methaemoglobin formation by Mycoplasma gallisepticum: the role of hydrogen peroxide. Factors associated with HIV/AIDS high-risk behaviours among female injection drug users. Influence of sire and sire breed (Gyr versus Holstein) on establishment of pregnancy and embryonic loss in lactating Holstein cows during summer heat stress. Prevalence of Clostridium perfringen (welchii) in the bovine udder

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Epinephrine modulates cellular distribution of muscle phosphofructokinase. The results of these studies indicated that nicotine gum, nicotine nasal spray and bupropion have a good safety profile and seem to increase abstinence rates in smokers with COPD. Thus, alpha-hydroxy acids directly enhanced the .OH generation via the Fenton reaction but not the Haber-Weiss reaction.

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In aquatic solutions containing both As(III) and Sb(III), the BFMO that formed in-situ preferentially oxidized Sb over As but adsorbed As more efficiently. We also find that alkanes, alcohols, and fullerene-type structures comprising n non-hydrogen atoms are uniquely characterized by signatures of height n/4, while peptides up to 4000 amino acids can be singled out with signatures of heights as small as 2 and 3. The novel strain of Bacillus thuringiensis J112 isolated from a soil sample in Jordan was classified and characterized in terms of toxicity against dipteran and nematode larvae, crystal protein pattern, plasmid profile, and cry gene content.

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Factors influencing pre-operative urinary calcium excretion in primary hyperparathyroidism. The result is the PSF from which we calculate the lateral resolution (LR). These findings provide useful health outcomes information to planners at the local level, for benchmarking purposes and to assist in resource allocation through the identification of differences in relative need between local populations. Preliminary results showed that the total concentrations of the target analytes ranged from 0.15 to 1.3 ng/g-lipid weight. The results also suggest that two reconstruction tunnels are needed to reconstruct the broad femoral attachment, whereas one reconstruction tunnel should be investigated further for the compact tibial attachment.

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Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame. In addition, information about diverse socio-demographic and professional variables were gathered. However, these methodologies are limited by their inability to reliably detect endogenously expressed peptides. Sixty-two women affected by locally advanced squamous cervical carcinoma treated with TP (paclitaxel 175 mg/m2 over a 3 h infusion plus cisplatin 75 mg/m2) or TIP (TP plus ifosphamide 5 mg/m2) were examined and scored according to the Total Neuropathy Score (TNS), before and during chemotherapy. These abnormalities may occur in children who developed only mild forms of retinopathy of prematurity during early life.

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